导师信息
博士生导师
硕士生导师
 
 
 
地址:青岛市市南区南海路7号
 
电话:0532-82898650

传真:0532-82898654

邮政编码:266071 

电子邮件:yjsb@ms.qdio.ac.cn
  








l  研究领域                    

基因组学、生物信息学                                                               

l  招生专业及方向

海洋生物学, 遗传学与遗传工程;基因组学     

l  联系方式                                                                                    

邮件:chenn@qdio.ac.cn

电话:0532-82893507

l  承担的主要科研项目

中国科学院百人计划(A类)

青岛海洋科学与技术国家实验室:利用第三代DNA测序技术研究赤潮发生机理                                                                                                                                                       

l  研究成果及奖励                                                                            

加拿大国家健康研究院青年学者奖

加拿大迈克司密斯健康研究基金会学者奖                                                  

代表性论文及著作

1)发表专著情况

《对虾生物学》,Dall等著,陈楠生等译,489页,青岛海洋大学出版社,1992

2)发表文章情况

共发表论文80余篇,如下是一些代表性论文。

1. Qin Z, Johnsen R, Yu S, Chu JSC, Baillie DL, and Chen. 2018. Genomic identification and functional characterization of essential genes in Caenorhabditis elegans. G3.

2. Dong L, Liu H, Zhang J, Yang S, Kong G, Chu JS, Chen N, Wang D, 2015. Single-molecule real-time transcript sequencing facilitates common wheat genome annotation and grain transcriptome research. BMC Genomics. 16:1039.

3. Zou S, Li J, Zhou H, Frech C, Jiang X, Chu JS, Zhao X, Li Y, Li Q, Wang H, Hu J, Kong G, Wu M, Ding C, Chen N, Hu H. 2014. Mutational landscape of intrahepatic cholangiocarcinoma. Nature Communications. 5:5696.

4. Uyar B, Chu JSC, Vergara IA, Chua SY, Jones MR, Wong T, Baillie, DL, and Chen N. 2012. RNA-seq analysis of C. briggsae transcriptome. Genome Research, 22(8)1567-1580.

5. Chu JSC, Tarailo-Graovac M, Zhang D, Wang J, Uyar B, Tu D, Trinh J, Baillie DL, and Chen N. 2012. Fine tuning of RFX/DAF-19-regulated target gene expression through binding to multiple sites in Caenorhabditis elegans. Nucleic Acids Research , 40(1):53-64.

6. Frech C and Chen N. 2011. Genome comparison of human and non-human malaria parasites reveals parasites-specific genes potentially linked to human disease. PLoS Computational Biology. 7(12): e1002320.

7. She R*, Chu JSC*, Uyar B, Wang J, Wang K, and Chen N. 2011. genBlastG: using BLAST searches to build homologous gene models. Bioinformatics. 27(15): 2141–2143.

8. She R*, Chu JSC*, Wang K, Pei J, Chen N. 2009. genBlastA: enabling BLAST to identify homologous gene sequences. Genome Research. 19: 143-149.

9. Chen N, Mah A, Blacque OE, Chu J, Phgora K, Khattra J, Chan S, Go A, Efimenko E, Johnsen R, Phirke P, Swoboda P, Marra M, Moerman DG, Leroux MR, Baillie DL, and Stein LD. 2006. Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Genome Biology, 7(12):R126.

10. Sea Urchin Genome Sequencing Consortium. 2006. The genome of the sea urchin Strongylocentrotus purpuratus. Science. 314(5801)

11. Chen N, Stein LD. 2006. Conservation and Functional Significance of Gene Topology in the Genome of Caenorhabditis elegans. Genome Research. 16:606-617.

12. Chen N, Pai S, Zhao Z, Mah A, Newbury R, Johnsen RC, Altun Z, Moerman DG, Baillie DL, Stein LD. 2005. Identification of a nematode chemosensory gene family. Proc Natl Acad Sci U S A. 102(1):146-51.

13. Chen N, Harris TW, Antoshechkin I, Bastiani C, Bieri T, Blasiar D, Bradnam K, Canaran P, Chan J, Chen CK, Chen WJ, Cunningham F, Davis P, Kenny E, Kishore R, Lawson D, Lee R, Muller HM, Nakamura C, Pai S, Ozersky P, Petcherski A, Rogers A, Sabo A, Schwarz EM, Van Auken K, Wang Q, Durbin R, Spieth J, Sternberg PW, Stein LD. 2005. WormBase: a comprehensive data resource for Caenorhabditis biology and genomics. Nucleic Acids Research 33(Database issue):D383-9.

14. Chen N, Lawson D, Bradnam K, Harris TW, Stein LD. 2004. WormBase as an integrated platform for the C. elegans ORFeome. Genome Research. 14(10B):2155-61.

15. Stein LD, Bao Z, Blasiar D, Blumenthal T, Brent MR, Chen N, Chinwalla A, Clarke L, Clee C, Coghlan A, Coulson A, D'Eustachio P, Fitch DH, Fulton LA, Fulton RE, Griffiths-Jones S, Harris TW, Hillier LW, Kamath R, Kuwabara PE, Mardis ER, Marra MA, Miner TL, Minx P, Mullikin JC, Plumb RW, Rogers J, Schein JE, Sohrmann M, Spieth J, Stajich JE, Wei C, Willey D, Wilson RK, Durbin R, Waterston RH. 2003. The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biology E45.